Manage Your Liver

Social jet lag: When the liver is out of sync

Social jet lag: When the liver is out of sync

Modern hectic lifestyle is causing most of us to live a life that is not in synchrony with our body’s biological clock. Busy work schedule, active social life, and accumulated fatigue are making us to stay awake when we are supposed to sleep, and sleep when we are supposed to be awake.

This leads to the development of a phenomenon called social jet lag, a condition that jeopardizes the liver's health to a tremendous degree.

Recently, more and more research begins to uncover the damage to the liver brought by this unhealthy lifestyle. It has been recognized that chronic social jet lag can increase liver cancer risk and accelerate the progression from non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH).


What exactly is social jet lag?

According to the National Center for Biotechnology Information, social jet lag, also known as chronic circadian disruption, refers to the discrepancy in behaviours between social and biological time, i.e. between work and free days. Oversleeping at weekends to compensate the sleep debt accumulated over the work week is a common example. Aside from the sleeping time, meal hours is heavily influenced by social jet lag as well.


How is the liver being affected?

The liver is a hardworking organ that works accordingly to our body’s internal clock. It is not difficult to imagine that when we are not sleeping or eating at the right time, its functions would be disrupted. Here’s how social jet lag plays a huge role in the progression of liver diseases.


  • Disrupts the liver’s functions & increases cancer risk

A recent research study published in the journal Cell Reports has found that meal times can influence the liver’s biological clock.

It is observed that disrupted biological clock can interfere with the liver’s production and synthesis of glucose, fat, cholesterol, and bile acid. In the study, subjects are put in chronic jet lag conditions and they are found to make more bile acids that are recycled back in the liver. An accumulation of excess bile acids can cause damage to liver cells and oxidative stress, which makes for a perfect condition for liver cancer to develop.


  • Accelerate NAFLD to NASH and fibrosis progression

When we delay our bedtime, there is a higher tendency to start late-night snacking. In another research study published in Cell Metabolism, it is found that nighttime eating caused a significant increase of about 25% of liver fat content. On the contrary, restricting nighttime snacking leads to a drastic decrease in liver fat content.

On top of the increase in liver fat content, jet-lagged subjects were found to show faster NAFLD to NASH progression. This is probably because irregular sleep-wake rhythm can induce persistent liver injury and liver inflammation, which can progress to liver cancer over time.

In fact, our liver health is so closely tied to our body’s natural internal clock that a new research study published in the journal Nature Communications suggests that, the body's internal clock could play a critical role in fighting against certain types of liver cancer.


Overcoming social jet lag for the liver

When it comes to protecting the liver from inflammation and diseases, liver supplements are useful and beneficial as they can safely repair and regenerate damaged liver cells, promote healthy liver functions, and lower the risks of developing advanced liver problems. But in the case of social jet lag, the liver’s health is compromised because of the unhealthy sleeping and eating habits.

Tips to a healthier liver? Try to maintain a similar eat and sleep schedule on work and free days. Avoid too much weekend lie-ins, or staying up too late at night. Most important of all, refrain from engaging late-night snacking as much as possible. The ultimate goal is to put our liver back in sync with our body’s natural clock.

  • * All research and clinical data should be used as reference purposes only, results may vary.
Related Questions
Liver issues, as one of the silent killers, seldom show distinct symptoms until scarring is formed on the liver, which is an advanced stage of liver damage. Yellowing of skin and eyes and persistent lack of energy are probably the most heard symptoms of liver problems. Besides these well-known symptoms, hair loss is also one of the warning signs of liver problem.   Normal follicle hair cycling requires proper uptake of fat-soluble vitamins, estrogen detoxification, an
  Japanese people are known for their longevity and low prevalence of chronic health issues. Japanese diet could be one of the secrets behind their long lifespan. The Japanese diet has been reported to be beneficial in preventing fat accumulation in liver cells.   Several ways of the Japanese diet protect liver health and let’s break it down.   Antioxidants and healthy fat In the Japanese diet, c
Hit Questions
The liver carries out essential functions, including detoxifying harmful substances in your body, cleaning your blood and making new blood and other vital nutrients. Cirrhosis is scarring of the liver caused by long-term liver damage. The loss of liver cells turns into scar tissue which prevents the liver working normally, reducing or in some cases, completely losing liver function. Cirrhosis is a long-term chronic liver damage; it is often caused by chronic live
ALT (Alanine Aminotransferase / SGPT) is an enzyme that is mainly found in liver cells. The level of ALT in our bloodstream is the primary indicator of liver health.   What does high ALT indicate? ALT enzymes are normally contained within liver cells when the liver is healthy, but when the liver cells are injured or damaged by whatever means, ALT enzymes are released into the bloodstream, causing levels to go up. Therefore, by measuring the
AST and ALT are two common markers for diagnosing liver diseases. Patients with liver disorders often find their AST and ALT levels unsatisfactory, but what do the figures actually imply? And do patients of every kind of liver dysfunctions have the same levels?   AST:ALT ratio Although the normal range of AST and ALT level varies among laboratories and countries, the ratio of AST:ALT is key when it comes to diagnosing liver diseases. The use
ALT (Alanine Aminotransferase / SGPT) is a type of enzyme found in liver cells. When the liver cells are functioning normally, the ALT enzymes should be contained within the liver cells.    You can imagine each liver cells as a balloon, and the ALT enzymes are the air inside the balloon. When the balloon is damaged, the air will be released. And when the liver cells is damaged, ALT enzymes are released into the bloodstream, therefore we are able to find out the l
YHK Liver Therapy
Your Liver

starts here.
Have Questions?
Sumbit your question to us for profeessional answers!
Looking for help? Ask our customer support team!
Contact Us
Subscribe To Our Mailing List And
Never Miss Another Great Promotion!
Join our mailing list to receive latest new about our company, plus health articles. You will also be able to receive early bird discount from us!
Maybe Later, Thank you.
Subscribe success! You will receive latest new soon.