Manage Your Liver
Q:

Social jet lag: When the liver is out of sync

Social jet lag: When the liver is out of sync
A:

Modern hectic lifestyle is causing most of us to live a life that is not in synchrony with our body’s biological clock. Busy work schedule, active social life, and accumulated fatigue are making us to stay awake when we are supposed to sleep, and sleep when we are supposed to be awake.

This leads to the development of a phenomenon called social jet lag, a condition that jeopardizes the liver's health to a tremendous degree.

Recently, more and more research begins to uncover the damage to the liver brought by this unhealthy lifestyle. It has been recognized that chronic social jet lag can increase liver cancer risk and accelerate the progression from non-alcoholic fatty liver disease (NAFLD) to non-alcoholic steatohepatitis (NASH).

 

What exactly is social jet lag?

According to the National Center for Biotechnology Information, social jet lag, also known as chronic circadian disruption, refers to the discrepancy in behaviours between social and biological time, i.e. between work and free days. Oversleeping at weekends to compensate the sleep debt accumulated over the work week is a common example. Aside from the sleeping time, meal hours is heavily influenced by social jet lag as well.

 

How is the liver being affected?

The liver is a hardworking organ that works accordingly to our body’s internal clock. It is not difficult to imagine that when we are not sleeping or eating at the right time, its functions would be disrupted. Here’s how social jet lag plays a huge role in the progression of liver diseases.

 

  • Disrupts the liver’s functions & increases cancer risk

A recent research study published in the journal Cell Reports has found that meal times can influence the liver’s biological clock.

It is observed that disrupted biological clock can interfere with the liver’s production and synthesis of glucose, fat, cholesterol, and bile acid. In the study, subjects are put in chronic jet lag conditions and they are found to make more bile acids that are recycled back in the liver. An accumulation of excess bile acids can cause damage to liver cells and oxidative stress, which makes for a perfect condition for liver cancer to develop.

 

  • Accelerate NAFLD to NASH and fibrosis progression

When we delay our bedtime, there is a higher tendency to start late-night snacking. In another research study published in Cell Metabolism, it is found that nighttime eating caused a significant increase of about 25% of liver fat content. On the contrary, restricting nighttime snacking leads to a drastic decrease in liver fat content.

On top of the increase in liver fat content, jet-lagged subjects were found to show faster NAFLD to NASH progression. This is probably because irregular sleep-wake rhythm can induce persistent liver injury and liver inflammation, which can progress to liver cancer over time.

In fact, our liver health is so closely tied to our body’s natural internal clock that a new research study published in the journal Nature Communications suggests that, the body's internal clock could play a critical role in fighting against certain types of liver cancer.

 

Overcoming social jet lag for the liver

When it comes to protecting the liver from inflammation and diseases, liver supplements are useful and beneficial as they can safely repair and regenerate damaged liver cells, promote healthy liver functions, and lower the risks of developing advanced liver problems. But in the case of social jet lag, the liver’s health is compromised because of the unhealthy sleeping and eating habits.

Tips to a healthier liver? Try to maintain a similar eat and sleep schedule on work and free days. Avoid too much weekend lie-ins, or staying up too late at night. Most important of all, refrain from engaging late-night snacking as much as possible. The ultimate goal is to put our liver back in sync with our body’s natural clock.

Disclaimer:
  • * All research and clinical data should be used as reference purposes only, results may vary.
Related Questions
A:
Decades before, fatty liver was considered a non-threatening disease because of its relatively rare occasions. As the economy continued to bloom in developed countries, modern style of living such as unhealthy food habits and sedentary lifestyle has taken its toll on our health, especially the liver. Non-alcoholic fatty liver disease (NAFLD) is a tricky condition to deal with because of its asymptomatic nature and its potential progression to serious liver problems. But now it is ev
A:
Sugar has a bad reputation, thanks to its well-known ability to cause type 2 diabetes and other health complications. While we know that excess sugar is bad for our health, have you ever thought about its effects on the liver? How do diets high in sugar influence our liver health? Do different types of sugars impact the liver the same way?   New study finds free sugars to be the culprit of NAFLD A new study published in JAMA, The
Hit Questions
A:
The liver carries out essential functions, including detoxifying harmful substances in your body, cleaning your blood and making new blood and other vital nutrients. Cirrhosis is scarring of the liver caused by long-term liver damage. The loss of liver cells turns into scar tissue which prevents the liver working normally, reducing or in some cases, completely losing liver function. Cirrhosis is a long-term chronic liver damage; it is often caused by chronic live
A:
ALT (Alanine Aminotransferase / SGPT) is an enzyme that is mainly found in liver cells. The level of ALT in our bloodstream is the primary indicator of liver health.   What does high ALT indicate? ALT enzymes are normally contained within liver cells when the liver is healthy, but when the liver cells are injured or damaged by whatever means, ALT enzymes are released into the bloodstream, causing levels to go up. Therefore, by measuring the
A:
ALT (Alanine Aminotransferase / SGPT) is a type of enzyme found in liver cells. When the liver cells are functioning normally, the ALT enzymes should be contained within the liver cells.    You can imagine each liver cells as a balloon, and the ALT enzymes are the air inside the balloon. When the balloon is damaged, the air will be released. And when the liver cells is damaged, ALT enzymes are released into the bloodstream, therefore we are able to find out the l
A:
Fibrosis is scarring of the liver that results from chronic inflammation. It is a process where the damaged, dying liver cells are replaced by fibrous scar tissue, causing the liver to become hard. The extent of liver fibrosis can vary, and it is often classified in several stages. The most common classification is a scale from F0 to F4. F0 indicates no fibrosis. A normal liver is at a stage between F0 and F1. F2 denotes light fibrosis, and F3 indicates severe fibrosis. When scar tissue build
YHK Liver Therapy
Your Liver
Protection

starts here.
Buy YHK
Have Questions?
Sumbit your question to us for profeessional answers!
Looking for help? Ask our customer support team!
Contact Us
Subscribe To Our Mailing List And
Never Miss Another Great Promotion!
Join our mailing list to receive latest new about our company, plus health articles. You will also be able to receive early bird discount from us!
Maybe Later, Thank you.
Subscribe success! You will receive latest new soon.