Managing cirrhosis – Reducing inflammation is key
Cirrhosis has always been a tricky liver condition to tackle, given its complications and symptoms that are difficult to manage. A recent study published in the American Journal of Physiology-Gastrointestinal and Liver Physiology mentions that lowering the inflammation level of cirrhosis patients’ oral cavity helps improve the overall inflammation level in the body, which could help minimize some of the symptoms cirrhosis patients experience. This study highlights the importance of managing the inflammation level when it comes to restoring liver health for cirrhosis patients.
Inflammation in cirrhosis patients
Since cirrhosis is a relatively serious stage of liver disease, patients do not just have inflammation in the liver, but systemic inflammation, which refers to inflammation throughout the whole body. According to a research published in the National Center for Biotechnology Information, systemic inflammation and immune system dysregulation are now considered the major factors involved in the progression of cirrhosis.
Problems that are caused by systemic inflammation in cirrhosis include but do not limit to portal hypertension, acute-on-chronic liver failure, hepatic encephalopathy, and infections.
Anti-inflammation is the solution
Various symptoms of cirrhosis develop because of the inflammation in the liver. The most practical and effective way is to target the root cause of the problem, in which case is the inflamed liver. By stopping hepatic inflammation, anti-inflammatory therapies do not only prevent further injury in the liver, but they also slow down or even put a stop to the progressive inflammation of other organs.
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- Semantic Scholar, https://www.semanticscholar.org/paper/Microbiota%2C-cirrhosis%2C-and-the-emerging-axis.-Acharya-Sahingur/ed10026605112931fefc7476ee4069c62bb669ac, (Accessed Date: 2018-09-11)
- National Center for Biotechnology Information, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528271/, (Accessed Date: 2018-09-11)
- National Center for Biotechnology Information, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631958/, (Accessed Date: 2018-09-11)
- Genetic Engineering & Biotechnology News, https://www.genengnews.com/gen-news-highlights/oral-microbiome-therapy-may-improve-cirrhosis-symptoms/81256187, (Accessed Date: 2018-09-11)
- * All research and clinical data should be used as reference purposes only, results may vary.