Manage Your Liver
Q:

How can we treat portal hypertension resulted from cirrhosis?

How can we treat portal hypertension resulted from cirrhosis?
A:

Being one of the serious stages of liver disease, cirrhosis has long been known as a difficult liver condition to deal with. Not only does the liver gradually cease to function because of the scar tissue, but the medical conditions developed from cirrhosis such as portal hypertension pose extra threats to patients’ prognosis. 

 

A promising approach to treat liver cirrhosis?

Portal hypertension has always been regarded as a condition that can only be managed, instead of treated. However, a recent study published in The American Journal of Pathology showed that treatment with aleglitazar, a type of agonists, helped improve the condition of portal hypertension by suppressing inflammation of the liver and relieving the constriction of blood vessels in subjects with cirrhosis. 

The study was carried out for 21 days and a number of beneficial changes were seen. Fibrosis was suppressed and constrictions of blood vessels were relieved, which greatly soothed the condition of portal hypertension. All these suggest treatments that contain anti-inflammatory properties could be an effective approach for managing cirrhosis.

 

What is portal hypertension?

As one of the major problems derived from cirrhosis, portal hypertension refers to the increased blood pressure in the veins leading to the liver due to the blockage of blood from the scar tissue. Because of the seriousness of this medical condition, portal hypertension accounts for the majority of medical complications and deaths associated with cirrhosis. 

In a healthy individual, blood flows freely from the liver to the other organs. But in cirrhosis patients with portal hypertension, as high pressure in the portal system gradually develops, veins in various parts of the body will become large and swollen. When the veins can no longer handle the pressure within, they can rupture and bleed which could cause life-threatening complications. Symptoms include gastrointestinal bleeding which results in black stools or vomiting of blood, and also ascites, which is the accumulation of fluid in the abdomen. 

 

Anti-inflammatory and anti-fibrotic therapy as a treatment method

Since portal hypertension is caused by the blockage of veins from the scar tissue in liver, reducing the degree of fibrosis would be one of the best ways to help tackle the problem.

In a research presented by Prof. Francesco Marotta at 14th Clinical Applications for Age Management Medicine that studied the use of nutraceuticals in chronic liver disease, a natural herbal compound was found to be able to reverse the stage of fibrosis. Subjects with cirrhosis were given the natural herbal compound as treatment. It was noticed that out of 6 groups of subjects, 4 showed a regression of fibrosis in their biopsy assessment, suggesting the positive effect of natural herbal compound on improving the condition of fibrosis. 

 

 

 

 

 

 

 

 

 

 

As fibrosis occurs because of the inflammation in the liver and the degree of inflammation can be reflected from liver enzyme levels such as AST and ALT, one of the effective ways of managing inflammation would be lowering the enzyme levels

In the same study, it was suggested that the same natural herbal compound reduced ALT level significantly without causing any known side-effects. In another research that focuses on the effect of the said natural herbal compound in patients of hepatic diseases, same promising results were also observed. After taking the treatment with the natural herbal compound for 10 days, the ALT and AST levels of the patients were remarkably lowered.

All these clinical researches suggest that by managing the liver enzyme levels and the degree of fibrosis, not only does it help relieve the condition of portal hypertension, but it also helps with treating cirrhosis, a liver condition that has long been known as an irreversible liver disease. 

If you have any questions regarding how we can help restore your liver health, please do not hesitate to contact our support team for more information about liver protection.

Disclaimer:
  • * All research and clinical data should be used as reference purposes only, results may vary.
Related Questions
A:
Nutrient deficiency has always been associated with some forms of illnesses and disorders. In a study conducted by Clinical Gastroenterology and Hepatology, it is revealed that over 90% of cirrhosis patients have vitamin D deficiency. And vitamin D deficiency is shown to be associated with the worsening of liver functions. How is low vitamin D level related to the progression of liver disease? In light of this phenomenon, should cirrhosis p
A:
According to the National Center for Biotechnology Information, there is increasing research data and clinical evidence showing that reversing fibrosis to a certain degree is now possible. This is a new hope for many liver disease patients, as fibrosis was once considered an untreatable condition. But what should be done, and how long does it take for us to achieve it?   The key to fibrosis reversal: Anti-fibrotic propertie
Hit Questions
A:
The liver carries out essential functions, including detoxifying harmful substances in your body, cleaning your blood and making new blood and other vital nutrients. Cirrhosis is scarring of the liver caused by long-term liver damage. The loss of liver cells turns into scar tissue which prevents the liver working normally, reducing or in some cases, completely losing liver function. Cirrhosis is a long-term chronic liver damage; it is often caused by chronic live
A:
ALT (Alanine Aminotransferase / SGPT) is an enzyme that is mainly found in liver cells. The level of ALT in our bloodstream is the primary indicator of liver health.   What does high ALT indicate? ALT enzymes are normally contained within liver cells when the liver is healthy, but when the liver cells are injured or damaged by whatever means, ALT enzymes are released into the bloodstream, causing levels to go up. Therefore, by measuring the
A:
AST and ALT are two common markers for diagnosing liver diseases. Patients with liver disorders often find their AST and ALT levels unsatisfactory, but what do the figures actually imply? And do patients of every kind of liver dysfunctions have the same levels?   AST:ALT ratio Although the normal range of AST and ALT level varies among laboratories and countries, the ratio of AST:ALT is key when it comes to diagnosing liver diseases. The use
A:
ALT (Alanine Aminotransferase / SGPT) is a type of enzyme found in liver cells. When the liver cells are functioning normally, the ALT enzymes should be contained within the liver cells.    You can imagine each liver cells as a balloon, and the ALT enzymes are the air inside the balloon. When the balloon is damaged, the air will be released. And when the liver cells is damaged, ALT enzymes are released into the bloodstream, therefore we are able to find out the l
YHK Liver Therapy
Your Liver
Protection

starts here.
Buy YHK
Have Questions?
Sumbit your question to us for profeessional answers!
Looking for help? Ask our customer support team!
Contact Us
Subscribe To Our Mailing List And
Never Miss Another Great Promotion!
Join our mailing list to receive latest new about our company, plus health articles. You will also be able to receive early bird discount from us!
Maybe Later, Thank you.
Subscribe success! You will receive latest new soon.