Manage Your Liver

I was diagnosed with NASH about six months ago. I have done a few liver function tests and my ALT level is constantly over the normal range at around 80~100. What exactly is ALT? How important is it for my ALT to stay normal? What can I do to lower my ALT?


ALT (or GPT) is a liver enzyme. Under normal circumstances, this enzyme resides within liver cells. But if the liver is injured, it will causes the liver cells to break and spill the enzymes into the blood stream, raising the enzyme level in the blood. [1] The level of ALT, along with another less significant liver enzyme – AST, are measured in blood tests called liver function tests (LFTs) to detect liver damage.

The normal value of ALT varies among different laboratories, but the common results should be around 10–40 IU/L. [2] An elevated ALT level usually signals liver damage. Long term liver damage and inflammation (as suggested by constantly high ALT) increases the risk of other liver problems. This is because when liver cells are injured, they can repair themselves; but when this happens excessively and repeatedly over time, liver cells may eventually die and scar tissues may form. This is known as fibrosis, which may advance to cirrhosis.

Some scientists found that elevated levels of ALT at or over 25 IU/L of blood were predictive of cancer risk. This is less than the 40 IU/L commonly defined as the upper limit of normal levels. [3] Therefore NASH patients should target to maintain a low ALT level and do regular checkups.

Currently, there is no conventional medical therapy to lower ALT level in NASH patients as the cause is not yet known. NASH patients are generally advised to follow a healthy diet and do exercise; if you are overweight or obese, losing weight may also help to reduce fat in the liver which may reduce ALT level. [4] Apart from these standard recommendations, NASH patients should also focus on protecting their liver and preventing progression of the disease.

A clinical study on PubMed suggests that YHK, a natural alternative therapy, has an inhibitory effect on the development of NASH; it has been proven to effectively reduce inflammation in the liver and help liver cells recover. Research shows that over 80% of patients’ ALT normalized within 2 weeks of using YHK. [5][6][7]

In addition, it is also important for NASH patients to avoid the use of alcohol and unnecessary medications as these may hurt the liver further.

  1. Liver Blood Tests. (2015). Retrieved from (accessed 12/10/2015)
  2. ALT. (2013). Retrieved from (accessed 13/10/2015)
  3. Common medical screen predicts liver cancer risk in general population. (2012). Retrieved from (accessed 17/10/2015)
  4. Nonalcoholic Steatohepatitis. (2006). Retrieved from (accessed 13/10/2015)
  5. Chande N, Laidlaw M, Adams P, Marotta P. (2006) “Yo Jyo Hen Shi Ko (YHK) improves transaminases in nonalcoholic steatohepatitis (NASH): a randomized pilot study” Digestive Diseases and Sciences Jul;51(7):1183-9. PMID: 16944007
  6. Stefano JT, de Oliveira CP, Corrêa-Giannella ML, de Lima VM, de Sá SV, de Oliveira EP, de Mello ES, Giannella-Neto D, Alves VA, Carrilho FJ. (2007) “Nonalcoholic steatohepatitis (NASH) in ob/ob mice treated with yo jyo hen shi ko (YHK): effects on peroxisome proliferator-activated receptors (PPARs) and microsomal triglyceride transfer protein (MTP)” Digestive Diseases and Sciences Dec;52(12):3448-54. PMID: 17394061
  7. de Lima VM, de Oliveira CP, Sawada LY, Barbeiro HV, de Mello ES, Soriano FG, Alves VA, Caldwell SH, Carrilho FJ. (2007) “Yo jyo hen shi ko, a novel Chinese herbal, prevents nonalcoholic steatohepatitis in ob/ob mice fed a high fat or methionine-choline-deficient diet” Liver International Mar;27(2):227-34. PMID: 17311618
  • * All research and clinical data should be used as reference purposes only, results may vary.
Related Questions
  Japanese people are known for their longevity and low prevalence of chronic health issues. Japanese diet could be one of the secrets behind their long lifespan. The Japanese diet has been reported to be beneficial in preventing fat accumulation in liver cells.   Several ways of the Japanese diet protect liver health and let’s break it down.   Antioxidants and healthy fat In the Japanese diet, c
Many of us know a healthy diet is one of the ways to protect our liver. But it is not just about eating the right food. It is also about eating in the right way. In 2015, research published in Population Health Management found that eating too fast and eating before sleep significantly impacts liver fat issues.   About 2000 participants were chosen among health insurance beneficiaries who were not identified as having liver fat problems. They completed physicals in 20
Hit Questions
The liver carries out essential functions, including detoxifying harmful substances in your body, cleaning your blood and making new blood and other vital nutrients. Cirrhosis is scarring of the liver caused by long-term liver damage. The loss of liver cells turns into scar tissue which prevents the liver working normally, reducing or in some cases, completely losing liver function. Cirrhosis is a long-term chronic liver damage; it is often caused by chronic live
ALT (Alanine Aminotransferase / SGPT) is an enzyme that is mainly found in liver cells. The level of ALT in our bloodstream is the primary indicator of liver health.   What does high ALT indicate? ALT enzymes are normally contained within liver cells when the liver is healthy, but when the liver cells are injured or damaged by whatever means, ALT enzymes are released into the bloodstream, causing levels to go up. Therefore, by measuring the
AST and ALT are two common markers for diagnosing liver diseases. Patients with liver disorders often find their AST and ALT levels unsatisfactory, but what do the figures actually imply? And do patients of every kind of liver dysfunctions have the same levels?   AST:ALT ratio Although the normal range of AST and ALT level varies among laboratories and countries, the ratio of AST:ALT is key when it comes to diagnosing liver diseases. The use
ALT (Alanine Aminotransferase / SGPT) is a type of enzyme found in liver cells. When the liver cells are functioning normally, the ALT enzymes should be contained within the liver cells.    You can imagine each liver cells as a balloon, and the ALT enzymes are the air inside the balloon. When the balloon is damaged, the air will be released. And when the liver cells is damaged, ALT enzymes are released into the bloodstream, therefore we are able to find out the l
YHK Liver Therapy
Your Liver

starts here.
Have Questions?
Sumbit your question to us for profeessional answers!
Looking for help? Ask our customer support team!
Contact Us
Subscribe To Our Mailing List And
Never Miss Another Great Promotion!
Join our mailing list to receive latest new about our company, plus health articles. You will also be able to receive early bird discount from us!
Maybe Later, Thank you.
Subscribe success! You will receive latest new soon.