Manage Your Liver

Malnutrition as an indirect cause of mortality in cirrhosis patients – Is it possible to prevent it?

Malnutrition as an indirect cause of mortality in cirrhosis patients – Is it possible to prevent it?

Cirrhosis patients often experience different problems derived from a malfunctioning liver, and malnutrition is one of the most common issues. As the liver has a key role in regulating the overall nutritional state and the energy balance, a liver that is not functioning properly will affect the body in various ways.

According to data from National Center for Biotechnology Information, on average, cirrhosis patients lose 7.7 ± 12.4 kg due to malnutrition and it gets worse with the severity of their underlying liver problem. Poor nutritional status is often associated with a bad prognosis as the risks of mortality and infection are higher.


A common, but difficult issue to tackle – why?

Malnutrition is a common problem in cirrhosis patients, affecting up to 60% of the patient population. There is not just a single cause that contributes to malnutrition, but rather the cause is multifactorial – various reasons that come from a malfunctioning liver contribute to this condition:

1) Inadequate intake of nutrients caused by

  • Loss of appetite due to the altered sense of taste or anorexia
  • Dietary restriction (e.g. low sodium)
  • Pain during eating
  • Generalised weakness and immobility
  • Poverty from the cost of cirrhosis treatments

2) Poor digestion and poor absorption caused by

  • Reduction in bile salt (which is used to digest fats)
  • Alcohol-related small bowel damage (food is passed down more quickly than usual)
  • Bacterial overgrowth

3) Increased energy expenditure caused by

  • Diarrhoea and bleeding that cause nutrient losses
  • A raised resting energy expenditure (requires more energy to do things)


Why do we have to tackle the problem of malnutrition?

Malnutrition contributes to a lot of the complications of cirrhosis as this problem affects different organs of the body. Even though it is still not sure if malnourished cirrhosis patients have a higher mortality rate or patients who pass away are more likely to be malnourished, it is clear that poor nutrition has a poor prognosis effect on cirrhosis patients. According to a research that studies the body composition and muscle function of cirrhosis patients, half of them are protein depleted and have reduced muscle function.


It’s a serious issue, but what can I do about it?

Current treatments for malnutrition includes following a nutritional recommendation, so that patients have a balanced intake of nutrients such as protein and vitamins, which are the major nutrients that most cirrhosis patients lack. Since the problem of malnutrition comes from a liver in bad condition, one of the most effective ways is to manage the health of the liver. When the health of the liver gradually improves, the problem of malabsorption, poor digestion, and loss of appetite will slowly go away. 

  • * All research and clinical data should be used as reference purposes only, results may vary.
Related Questions
Nutrient deficiency has always been associated with some forms of illnesses and disorders. In a study conducted by Clinical Gastroenterology and Hepatology, it is revealed that over 90% of cirrhosis patients have vitamin D deficiency. And vitamin D deficiency is shown to be associated with the worsening of liver functions. How is low vitamin D level related to the progression of liver disease? In light of this phenomenon, should cirrhosis p
According to the National Center for Biotechnology Information, there is increasing research data and clinical evidence showing that reversing fibrosis to a certain degree is now possible. This is a new hope for many liver disease patients, as fibrosis was once considered an untreatable condition. But what should be done, and how long does it take for us to achieve it?   The key to fibrosis reversal: Anti-fibrotic propertie
Hit Questions
The liver carries out essential functions, including detoxifying harmful substances in your body, cleaning your blood and making new blood and other vital nutrients. Cirrhosis is scarring of the liver caused by long-term liver damage. The loss of liver cells turns into scar tissue which prevents the liver working normally, reducing or in some cases, completely losing liver function. Cirrhosis is a long-term chronic liver damage; it is often caused by chronic live
ALT (Alanine Aminotransferase / SGPT) is an enzyme that is mainly found in liver cells. The level of ALT in our bloodstream is the primary indicator of liver health.   What does high ALT indicate? ALT enzymes are normally contained within liver cells when the liver is healthy, but when the liver cells are injured or damaged by whatever means, ALT enzymes are released into the bloodstream, causing levels to go up. Therefore, by measuring the
AST and ALT are two common markers for diagnosing liver diseases. Patients with liver disorders often find their AST and ALT levels unsatisfactory, but what do the figures actually imply? And do patients of every kind of liver dysfunctions have the same levels?   AST:ALT ratio Although the normal range of AST and ALT level varies among laboratories and countries, the ratio of AST:ALT is key when it comes to diagnosing liver diseases. The use
ALT (Alanine Aminotransferase / SGPT) is a type of enzyme found in liver cells. When the liver cells are functioning normally, the ALT enzymes should be contained within the liver cells.    You can imagine each liver cells as a balloon, and the ALT enzymes are the air inside the balloon. When the balloon is damaged, the air will be released. And when the liver cells is damaged, ALT enzymes are released into the bloodstream, therefore we are able to find out the l
YHK Liver Therapy
Your Liver

starts here.
Have Questions?
Sumbit your question to us for profeessional answers!
Looking for help? Ask our customer support team!
Contact Us
Subscribe To Our Mailing List And
Never Miss Another Great Promotion!
Join our mailing list to receive latest new about our company, plus health articles. You will also be able to receive early bird discount from us!
Maybe Later, Thank you.
Subscribe success! You will receive latest new soon.